Skip to content
GenoLensGenoLens

CCR7

Chr 17q21.2

C-C motif chemokine receptor 7

Aliases:
BLR2, CDw197, CD197
MANE:
ENST00000246657.2
OMIM: 600242 ↗NCBI: 1236 ↗Ensembl ↗

Annotations refreshed 9 hours ago.

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Moderate Evidence (Amber)

  • COVID-19 research

    Unknown

Disease associations (Open Targets)

  • neurodegenerative disease

    0.32

  • Alzheimer disease

    0.25

  • breast carcinoma

    0.21

  • B-cell chronic lymphocytic leukemia

    0.21

  • hepatocellular carcinoma

    0.21

  • esophageal squamous cell carcinoma

    0.21

  • head and neck squamous cell carcinoma

    0.21

  • prostate carcinoma

    0.21

  • melanoma

    0.20

  • lung adenocarcinoma

    0.20

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)

C-C chemokine receptor type 7

Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions

Data sources: HGNC (CC BY 4.0), AlphaFold (CC BY 4.0, Jumper et al. Nature 2021), Genomics England PanelApp (CC BY 4.0), ClinGen, Open Targets (CC0), UniProt.

Not for sole clinical decision-making. Always verify against primary sources.