CDKN2A

Chr 9p21.3

cyclin dependent kinase inhibitor 2A

Aliases:: CDK4I, p16, INK4a, MTS1, CMM2
MANE:: ENST00000304494.10

OMIM: 600160 ↗NCBI: 1029 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

CDKN2A · P42771

v62025-08-01

Predicted Aligned Error matrix for CDKN2A — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

76.3/ 100

Confident

156 residues

Confidence breakdown

Very high(≥ 90)1%
Confident(70–90)75%
Low(50–70)11%
Very low(< 50)13%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.