CEACAM16

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Monogenic hearing loss

  BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Disease associations (Open Targets)

• hearing loss, autosomal recessive

  0.61

• autosomal dominant nonsyndromic hearing loss

  0.60

• nonsyndromic genetic hearing loss

  0.52

• Non-syndromic genetic deafness

  0.43

• Sensorineural hearing impairment

  0.40

• deafness

  0.37

• hearing loss disorder

  0.34

• Abnormality of the ear

  0.28

• Rare genetic deafness

  0.28

• ear malformation

  0.27

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)