AlphaFold predicted structure
CELA3B · P08861
Mean pLDDT
90.8/ 100
Very high
270 residues
Confidence breakdown
- Very high(≥ 90)85%
- Confident(70–90)4%
- Low(50–70)3%
- Very low(< 50)9%
Open interactive 3D viewer
AlphaFold (Jumper et al., 2021) · CC BY 4.0
CELA3B
Chr 1p36.12chymotrypsin like elastase 3B
- Aliases:
- CBPP
- MANE:
- ENST00000337107.11
Annotations refreshed 1 month ago.
Predicted protein structure
Clinical relevance (Genomics England PanelApp)
Diagnostic Grade (Green)
Pancreatitis
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Disease associations (Open Targets)
chronic pancreatitis
0.38diabetes mellitus
0.37pancreatic neoplasm
0.37familial pancreatic carcinoma
0.37atrial fibrillation
0.27Crohn disease
0.24atrial flutter
0.21inflammatory bowel disease
0.18COVID-19
0.18hypertensive disorder
0.17
Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.
Protein function (UniProt)
Chymotrypsin-like elastase family member 3B
Efficient protease with alanine specificity but only little elastolytic activity
Diseases associated with CELA3B
Curated MONDO disease pages that list CELA3B among their top associated genes.