ERCC2

Chr 19q13.32

ERCC excision repair 2, TFIIH core complex helicase subunit

Aliases:: MAG, EM9, MGC102762, MGC126218, MGC126219
MANE:: ENST00000391945.10

OMIM: 126340 ↗NCBI: 2068 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

ERCC2 · P18074

v62025-08-01

Predicted Aligned Error matrix for ERCC2 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

87.6/ 100

Confident

760 residues

Confidence breakdown

Very high(≥ 90)54%
Confident(70–90)41%
Low(50–70)4%
Very low(< 50)1%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.