FGF10

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• DDG2P

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Deafness and congenital structural abnormalities

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• Fetal anomalies

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Limb disorders

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Radial dysplasia

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Skeletal dysplasia

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• VACTERL-like phenotypes

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• Rare syndromic craniosynostosis or isolated multisuture synostosis

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

+1 more panels — install the extension to see the full list inline on any page.

Disease associations (Open Targets)

• Lacrimoauriculodentodigital syndrome

  0.72

• lacrimoauriculodentodigital syndrome 3

  0.69

• LADD syndrome

  0.69

• aplasia of lacrimal and salivary glands

  0.64

• cancer

  0.61

• bone development disease

  0.58

• LADD syndrome 1

  0.57

• female reproductive endometrioid cancer

  0.50

• ovarian carcinoma

  0.46

• prostate carcinoma

  0.43

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)