FGF20

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Moderate Evidence (Amber)

• CAKUT

  BIALLELIC, autosomal or pseudoautosomal

• Fetal anomalies

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• cancer

  0.60

• bone development disease

  0.60

• renal hypodysplasia/aplasia 2

  0.40

• bilateral renal agenesis

  0.38

• craniosynostosis

  0.38

• renal agenesis

  0.37

• ovarian carcinoma

  0.37

• female reproductive endometrioid cancer

  0.37

• acrocephalosyndactyly

  0.37

• Parkinson disease

  0.34

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)