FKBP10

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Arthrogryposis

  BIALLELIC, autosomal or pseudoautosomal

• DDG2P

  BIALLELIC, autosomal or pseudoautosomal

• Fetal anomalies

  BIALLELIC, autosomal or pseudoautosomal

• Osteogenesis imperfecta

  BIALLELIC, autosomal or pseudoautosomal

• Skeletal dysplasia

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• Bruck syndrome

  0.80

• osteogenesis imperfecta

  0.70

• arthrogryposis-like syndrome

  0.60

• osteogenesis imperfecta type 3

  0.46

• osteogenesis imperfecta, recessive

  0.46

• skeletal dysplasia

  0.46

• hereditary disease

  0.42

• osteogenesis imperfecta type 4

  0.37

• Abnormality of the skeletal system

  0.35

• neurodegenerative disease

  0.21

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)

Diseases associated with FKBP10

Curated MONDO disease pages that list FKBP10 among their top associated genes.

• nonpapillary renal cell carcinomaRare