FRY

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Moderate Evidence (Amber)

• Intellectual disability

  BIALLELIC, autosomal or pseudoautosomal

• DDG2P

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• schizophrenia

  0.38

• smoking initiation

  0.33

• liver disorder

  0.28

• glomerulonephritis

  0.27

• ankylosing spondylitis

  0.27

• hypothyroidism

  0.25

• complication

  0.21

• medical procedure

  0.21

• autosomal recessive non-syndromic intellectual disability

  0.18

• placenta praevia

  0.17

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)