FTO

Chr 16q12.2

FTO alpha-ketoglutarate dependent dioxygenase

Aliases:: KIAA1752, MGC5149, ALKBH9, IFEX9
MANE:: ENST00000471389.6

OMIM: 610966 ↗NCBI: 79068 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

FTO · Q9C0B1

v62025-08-01

Predicted Aligned Error matrix for FTO — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

91.0/ 100

Very high

505 residues

Confidence breakdown

Very high(≥ 90)80%
Confident(70–90)12%
Low(50–70)4%
Very low(< 50)5%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.