GRXCR1

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Monogenic hearing loss

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• hearing loss, autosomal recessive

  0.71

• deafness

  0.57

• Rare genetic deafness

  0.42

• Non-syndromic genetic deafness

  0.39

• hearing loss disorder

  0.37

• nonsyndromic genetic hearing loss

  0.37

• alopecia areata

  0.34

• malignant renal pelvis neoplasm

  0.32

• cardiomyopathy

  0.29

• Hearing impairment

  0.27

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)