HPS1

Chr 10q24.2

HPS1 biogenesis of lysosomal organelles complex 3 subunit 1

Aliases:: BLOC3S1
MANE:: ENST00000361490.9

OMIM: 604982 ↗NCBI: 3257 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

HPS1 · Q92902

v62025-08-01

Predicted Aligned Error matrix for HPS1 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

80.6/ 100

Confident

700 residues

Confidence breakdown

Very high(≥ 90)54%
Confident(70–90)25%
Low(50–70)6%
Very low(< 50)15%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.