HPS4

Chr 22q12.1

HPS4 biogenesis of lysosomal organelles complex 3 subunit 2

Aliases:: KIAA1667, LE, BLOC3S2
MANE:: ENST00000398145.7

OMIM: 606682 ↗NCBI: 89781 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

HPS4 · Q9NQG7

v62025-08-01

Predicted Aligned Error matrix for HPS4 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

61.7/ 100

Low

708 residues

Confidence breakdown

Very high(≥ 90)30%
Confident(70–90)23%
Low(50–70)3%
Very low(< 50)43%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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