HSD17B4

Chr 5q23.1

hydroxysteroid 17-beta dehydrogenase 4

Aliases:: MFE-2, DBP, SDR8C1
MANE:: ENST00000510025.7

OMIM: 601860 ↗NCBI: 3295 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

HSD17B4 · P51659

v62025-08-01

Predicted Aligned Error matrix for HSD17B4 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

89.0/ 100

Confident

736 residues

Confidence breakdown

Very high(≥ 90)67%
Confident(70–90)24%
Low(50–70)5%
Very low(< 50)4%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.