IDH1

Chr 2q34

isocitrate dehydrogenase (NADP(+)) 1

MANE:: ENST00000345146.7

OMIM: 147700 ↗NCBI: 3417 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

IDH1 · O75874

v62025-08-01

Predicted Aligned Error matrix for IDH1 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

95.9/ 100

Very high

414 residues

Confidence breakdown

Very high(≥ 90)95%
Confident(70–90)5%
Low(50–70)1%
Very low(< 50)0%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.