KCNQ1OT1
Chr 11p15.5KCNQ1 opposite strand/antisense transcript 1
- Aliases:
- KvDMR1, KCNQ1-AS2, KvLQT1-AS, LIT1, NCRNA00012
- MANE:
- ENST00000597346.1
Annotations refreshed 9 hours ago.
Predicted protein structure
No predicted 3D structure for KCNQ1OT1. Non-coding genes and pseudogenes typically have no protein product.
Clinical relevance (Genomics England PanelApp)
Moderate Evidence (Amber)
Beckwith-Wiedemann syndrome (BWS) and other congenital overgrowth disorders
MONOALLELIC, autosomal or pseudoautosomal, paternally imprinted (maternal allele expressed)Childhood solid tumours
Disease associations (Open Targets)
isolated hemihyperplasia
0.37Hemihypertrophy
0.37Beckwith-Wiedemann syndrome
0.20colorectal carcinoma
0.11neoplasm
0.11hepatocellular carcinoma
0.11gastric cancer
0.11breast cancer
0.10osteosarcoma
0.10non-small cell lung carcinoma
0.10
Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.