KIAA0825

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Limb disorders

  BIALLELIC, autosomal or pseudoautosomal

• Fetal anomalies

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• polydactyly, postaxial, type a10

  0.63

• postaxial polydactyly

  0.44

• polydactyly, postaxial, type A1

  0.42

• alcohol drinking

  0.39

• postaxial polydactyly type A

  0.37

• atrial fibrillation

  0.33

• stroke disorder

  0.31

• Vertigo

  0.29

• ovarian neoplasm

  0.27

• urinary tract obstruction

  0.26

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.