LINGO4

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Intellectual disability

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• speech disorder

  0.37

• Intellectual disability

  0.37

• asthma

  0.30

• polymicrogyria

  0.15

• insomnia

  0.08

• ulcerative colitis

  0.05

• inflammatory bowel disease

  0.05

• coronary artery disorder

  0.05

• lower respiratory tract disorder

  0.04

• deep vein thrombosis

  0.04

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.