MIR17HG

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• DDG2P

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Fetal anomalies

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Intellectual disability

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Limb disorders

• Severe microcephaly

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Skeletal dysplasia

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• VACTERL-like phenotypes

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Disease associations (Open Targets)

• Feingold syndrome type 2

  0.63

• Feingold syndrome

  0.54

• Feingold syndrome type 1

  0.53

• Intellectual disability

  0.23

• colorectal carcinoma

  0.09

• breast cancer

  0.08

• breast carcinoma

  0.08

• central nervous system cancer

  0.08

• glioma

  0.08

• retinoblastoma

  0.07

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.