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MIR204

Chr 9q21.12

microRNA 204

Aliases:
hsa-mir-204

Annotations refreshed 9 hours ago.

Predicted protein structure

No predicted 3D structure for MIR204. Non-coding genes and pseudogenes typically have no protein product.

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

  • Retinal disorders

    MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
  • Structural eye disease

    MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
  • Ocular coloboma

    MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Disease associations (Open Targets)

  • familial progressive retinal dystrophy-iris coloboma-congenital cataract syndrome

    0.66
  • early-onset non-syndromic cataract

    0.12
  • Total congenital cataract

    0.11
  • Posterior polar cataract

    0.11
  • early-onset zonular cataract

    0.11
  • Partial congenital cataract

    0.11
  • early-onset nuclear cataract

    0.11
  • Cataract with Y-shaped suture opacities

    0.10
  • Cataract-microcornea syndrome

    0.10
  • Anterior polar cataract

    0.10

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Data sources: HGNC (CC BY 4.0), AlphaFold (CC BY 4.0, Jumper et al. Nature 2021), Genomics England PanelApp (CC BY 4.0), ClinGen, Open Targets (CC0), UniProt.

Not for sole clinical decision-making. Always verify against primary sources.