MLH1

Chr 3p22.2

mutL homolog 1

Aliases:: HNPCC, FCC2, HNPCC2, MLH-1
MANE:: ENST00000231790.8

OMIM: 120436 ↗NCBI: 4292 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

MLH1 · P40692

v62025-08-01

Predicted Aligned Error matrix for MLH1 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

77.3/ 100

Confident

756 residues

Confidence breakdown

Very high(≥ 90)51%
Confident(70–90)23%
Low(50–70)6%
Very low(< 50)20%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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