MPL

Chr 1p34.2

MPL proto-oncogene, thrombopoietin receptor

Aliases:: CD110, TPOR, THPOR
MANE:: ENST00000372470.9

OMIM: 159530 ↗NCBI: 4352 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

MPL · P40238

v62025-08-01

Predicted Aligned Error matrix for MPL — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

72.7/ 100

Confident

635 residues

Confidence breakdown

Very high(≥ 90)32%
Confident(70–90)35%
Low(50–70)11%
Very low(< 50)23%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.