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MT-RNR2

Chr mitochondria

mitochondrially encoded 16S rRNA

Aliases:
HN, 16S
OMIM: 561010 ↗NCBI: 4550 ↗Ensembl ↗

Annotations refreshed 9 hours ago.

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Moderate Evidence (Amber)

  • Likely inborn error of metabolism

    MITOCHONDRIAL

  • Mitochondrial disorders

    MITOCHONDRIAL

  • Childhood onset dystonia, chorea or related movement disorder

    MITOCHONDRIAL

Disease associations (Open Targets)

  • glioblastoma

    0.10

  • Parkinson disease

    0.09

  • age-related macular degeneration

    0.09

  • posterior cortical atrophy

    0.08

  • adrenal cortex carcinoma

    0.07

  • neoplasm

    0.07

  • inflammatory bowel disease

    0.07

  • breast cancer

    0.07

  • familial isolated dilated cardiomyopathy

    0.06

  • hypertrophic cardiomyopathy

    0.06

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)

Small humanin-like peptide 6

Significantly increases apoptosis in vitro

Data sources: HGNC (CC BY 4.0), AlphaFold (CC BY 4.0, Jumper et al. Nature 2021), Genomics England PanelApp (CC BY 4.0), ClinGen, Open Targets (CC0), UniProt.

Not for sole clinical decision-making. Always verify against primary sources.