MT-TI

Chr mitochondria

mitochondrially encoded tRNA-Ile (AUU/C)

Aliases:: trnI

OMIM: 590045 ↗NCBI: 4565 ↗Ensembl ↗

Annotations refreshed 10 hours ago.

Predicted protein structure

No predicted 3D structure for MT-TI. Non-coding genes and pseudogenes typically have no protein product.

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

Likely inborn error of metabolism
MITOCHONDRIAL
Mitochondrial disorders
MITOCHONDRIAL
Paediatric or syndromic cardiomyopathy
MITOCHONDRIAL
Undiagnosed metabolic disorders
MITOCHONDRIAL
Hypertrophic cardiomyopathy
MITOCHONDRIAL
Childhood onset dystonia, chorea or related movement disorder
MITOCHONDRIAL

Disease associations (Open Targets)

hypertrophic cardiomyopathy
0.58
familial hypertrophic cardiomyopathy
0.53
familial dilated cardiomyopathy
0.53
inborn mitochondrial metabolism disorder
0.37
mitochondrial disease
0.37
breast carcinoma
0.03
ulcerative colitis
0.02
sclerosing cholangitis
0.02
schizophrenia
0.01
autism
0.01

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.