Skip to content
GenoLensGenoLens

MT-TP

Chr mitochondria

mitochondrially encoded tRNA-Pro (CCN)

Aliases:
trnP
OMIM: 590075 ↗NCBI: 4571 ↗Ensembl ↗

Annotations refreshed 10 hours ago.

Predicted protein structure

No predicted 3D structure for MT-TP. Non-coding genes and pseudogenes typically have no protein product.

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

  • DDG2P

    MITOCHONDRIAL

  • Likely inborn error of metabolism

    MITOCHONDRIAL

  • Mitochondrial disorders

    MITOCHONDRIAL

  • Undiagnosed metabolic disorders

    MITOCHONDRIAL

  • Congenital myopathy

    MITOCHONDRIAL

  • Retinal disorders

    MITOCHONDRIAL

  • Fetal anomalies

    MITOCHONDRIAL

  • Intellectual disability

    MITOCHONDRIAL

+1 more panels — install the extension to see the full list inline on any page.

Disease associations (Open Targets)

  • MERRF

    0.50

  • MERRF syndrome

    0.46

  • inborn mitochondrial metabolism disorder

    0.37

  • mitochondrial disease

    0.37

  • inborn mitochondrial myopathy

    0.18

  • fatty liver disease

    0.09

  • Hepatic steatosis

    0.09

  • glioblastoma

    0.08

  • brain neoplasm

    0.07

  • metabolic dysfunction-associated steatotic liver disease

    0.07

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Data sources: HGNC (CC BY 4.0), AlphaFold (CC BY 4.0, Jumper et al. Nature 2021), Genomics England PanelApp (CC BY 4.0), ClinGen, Open Targets (CC0), UniProt.

Not for sole clinical decision-making. Always verify against primary sources.