MTHFR

Chr 1p36.22

methylenetetrahydrofolate reductase

MANE:: ENST00000376590.9

OMIM: 607093 ↗NCBI: 4524 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

MTHFR · P42898

v62025-08-01

Predicted Aligned Error matrix for MTHFR — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

88.6/ 100

Confident

656 residues

Confidence breakdown

Very high(≥ 90)76%
Confident(70–90)13%
Low(50–70)4%
Very low(< 50)7%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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