NUP88

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Moderate Evidence (Amber)

• Arthrogryposis

  BIALLELIC, autosomal or pseudoautosomal

• Fetal anomalies

  BIALLELIC, autosomal or pseudoautosomal

• COVID-19 research

Disease associations (Open Targets)

• fetal akinesia deformation sequence 1

  0.66

• HIV infectious disease

  0.54

• influenza

  0.54

• viral infectious disease

  0.53

• fetal akinesia deformation sequence

  0.38

• COVID-19

  0.37

• Histiocytosis

  0.37

• neurodegenerative disease

  0.33

• Alzheimer disease

  0.32

• Parkinson disease

  0.31

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)

Diseases associated with NUP88

Curated MONDO disease pages that list NUP88 among their top associated genes.

• viral infectious diseaseRare