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GenoLensGenoLens

OGFRL1

Chr 6q13

opioid growth factor receptor like 1

Aliases:
dJ331H24.1
MANE:
ENST00000370435.5

Annotations refreshed 1 month ago.

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Moderate Evidence (Amber)

  • Autoinflammatory disorders

    BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

  • ovarian neoplasm

    0.41
  • prostate carcinoma

    0.35
  • hypertensive disorder

    0.20
  • cherubism

    0.19
  • hearing loss disorder

    0.18
  • chronic hepatitis

    0.15
  • stroke disorder

    0.15
  • occlusion precerebral artery

    0.15
  • response to xenobiotic stimulus

    0.15
  • Parkinson disease

    0.13

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Curated MONDO disease pages that list OGFRL1 among their top associated genes.

Data sources: HGNC (CC BY 4.0), AlphaFold (CC BY 4.0, Jumper et al. Nature 2021), Genomics England PanelApp (CC BY 4.0), ClinGen, Open Targets (CC0), UniProt.

Not for sole clinical decision-making. Always verify against primary sources.