PCSK9

Chr 1p32.3

proprotein convertase subtilisin/kexin type 9

Aliases:: NARC-1, FH3
MANE:: ENST00000302118.5

OMIM: 607786 ↗NCBI: 255738 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

PCSK9 · Q8NBP7

v62025-08-01

Predicted Aligned Error matrix for PCSK9 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

85.2/ 100

Confident

692 residues

Confidence breakdown

Very high(≥ 90)67%
Confident(70–90)15%
Low(50–70)5%
Very low(< 50)14%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.