PITX2

Chr 4q25

paired like homeodomain 2

Aliases:: IGDS, RS, Brx1, Otlx2, ARP1
MANE:: ENST00000644743.1

OMIM: 601542 ↗NCBI: 5308 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

PITX2 · Q99697

v62025-08-01

Predicted Aligned Error matrix for PITX2 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

61.3/ 100

Low

317 residues

Confidence breakdown

Very high(≥ 90)17%
Confident(70–90)9%
Low(50–70)37%
Very low(< 50)37%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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