POLE2

Chr 14q21.3

DNA polymerase epsilon 2, accessory subunit

Aliases:: DPE2
MANE:: ENST00000216367.10

OMIM: 602670 ↗NCBI: 5427 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

POLE2 · P56282

v62025-08-01

Predicted Aligned Error matrix for POLE2 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

93.0/ 100

Very high

527 residues

Confidence breakdown

Very high(≥ 90)81%
Confident(70–90)15%
Low(50–70)3%
Very low(< 50)1%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.