POLG

Chr 15q26.1

DNA polymerase gamma, catalytic subunit

Aliases:: POLG1, POLGA
MANE:: ENST00000268124.11

OMIM: 174763 ↗NCBI: 5428 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

POLG · P54098

v62025-08-01

Predicted Aligned Error matrix for POLG — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

78.9/ 100

Confident

1,239 residues

Confidence breakdown

Very high(≥ 90)43%
Confident(70–90)35%
Low(50–70)6%
Very low(< 50)16%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.