PRPS1

Chr Xq22.3

phosphoribosyl pyrophosphate synthetase 1

Aliases:: CMTX5, DFNX1, PRS-I, PPRibP
MANE:: ENST00000372435.10

OMIM: 311850 ↗NCBI: 5631 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

PRPS1 · P60891

v62025-08-01

Predicted Aligned Error matrix for PRPS1 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

94.8/ 100

Very high

318 residues

Confidence breakdown

Very high(≥ 90)90%
Confident(70–90)7%
Low(50–70)3%
Very low(< 50)1%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.