PSEN1

Chr 14q24.2

presenilin 1

Aliases:: FAD, S182, PS1, PS-1, PSNL1
MANE:: ENST00000324501.10

OMIM: 104311 ↗NCBI: 5663 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

PSEN1 · P49768

v62025-08-01

Predicted Aligned Error matrix for PSEN1 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

72.1/ 100

Confident

467 residues

Confidence breakdown

Very high(≥ 90)36%
Confident(70–90)25%
Low(50–70)12%
Very low(< 50)27%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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