PSEN2

Chr 1q42.13

presenilin 2

Aliases:: AD3L, STM2, PS2, PS-2, E5-1
MANE:: ENST00000366783.8

OMIM: 600759 ↗NCBI: 5664 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

PSEN2 · P49810

v62025-08-01

Predicted Aligned Error matrix for PSEN2 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

71.8/ 100

Confident

448 residues

Confidence breakdown

Very high(≥ 90)38%
Confident(70–90)26%
Low(50–70)7%
Very low(< 50)29%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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