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RNU6-1

Chr 15q23

RNA, U6 small nuclear 1

Aliases:
U6, U6-1
MANE:
ENST00000383898.1
OMIM: 180692 ↗NCBI: 26827 ↗Ensembl ↗

Annotations refreshed 9 hours ago.

Predicted protein structure

No predicted 3D structure for RNU6-1. Non-coding genes and pseudogenes typically have no protein product.

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

  • Retinal disorders

    MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Disease associations (Open Targets)

  • retinitis pigmentosa

    0.37

  • glioblastoma

    0.05

  • retinitis pigmentosa 1

    0.02

  • primary central nervous system lymphoma

    0.02

  • type 2 diabetes mellitus

    0.02

  • Blindness

    0.01

  • blindness (disorder)

    0.01

  • hereditary disease

    0.01

  • Alzheimer disease

    0.01

  • autosomal dominant retinitis pigmentosa

    0.01

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Data sources: HGNC (CC BY 4.0), AlphaFold (CC BY 4.0, Jumper et al. Nature 2021), Genomics England PanelApp (CC BY 4.0), ClinGen, Open Targets (CC0), UniProt.

Not for sole clinical decision-making. Always verify against primary sources.