AlphaFold predicted structure
RP9 · Q8TA86
Mean pLDDT
77.8/ 100
Confident
221 residues
Confidence breakdown
- Very high(≥ 90)21%
- Confident(70–90)55%
- Low(50–70)12%
- Very low(< 50)12%
Open interactive 3D viewer
AlphaFold (Jumper et al., 2021) · CC BY 4.0
RP9
Chr 7p14.3RP9 pre-mRNA splicing factor
- Aliases:
- PAP-1
- MANE:
- ENST00000297157.8
Annotations refreshed 9 hours ago.
Predicted protein structure
Clinical relevance (Genomics England PanelApp)
Diagnostic Grade (Green)
Retinal disorders
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknownGlaucoma (developmental)
Structural eye disease
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Disease associations (Open Targets)
retinitis pigmentosa
0.66retinitis pigmentosa 9
0.58Abnormality of the skeletal system
0.44autosomal dominant retinitis pigmentosa
0.38eye disorder
0.37neurodegenerative disease
0.31Retinal dystrophy
0.18optic atrophy
0.11obesity disorder
0.08leprosy
0.07
Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.
Protein function (UniProt)
Retinitis pigmentosa 9 protein
Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1 (By similarity)