RPS26

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Clefting

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Cytopenia - NOT Fanconi anaemia

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• Cytopenias and congenital anaemias

  MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

• DDG2P

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Fetal anomalies

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Haematological malignancies cancer susceptibility

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Haematological malignancies for rare disease

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

• Limb disorders

  MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

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Disease associations (Open Targets)

• Blackfan-Diamond anemia

  0.83

• Diamond-Blackfan anemia

  0.76

• inherited bone marrow failure syndrome

  0.50

• Duchenne muscular dystrophy

  0.50

• influenza

  0.46

• acute myeloid leukemia with minimal differentiation

  0.46

• asthma

  0.44

• type 1 diabetes mellitus

  0.40

• COVID-19

  0.39

• cystic fibrosis

  0.39

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)

Diseases associated with RPS26

Curated MONDO disease pages that list RPS26 among their top associated genes.

• severe acute respiratory syndromeRare