SETD2

Chr 3p21.31

SET domain containing 2, histone lysine methyltransferase

Aliases:: HYPB, HIF-1, KIAA1732, FLJ23184, KMT3A
MANE:: ENST00000409792.4

OMIM: 612778 ↗NCBI: 29072 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

SETD2 · Q9BYW2

v62025-08-01

Predicted Aligned Error matrix for SETD2 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

43.3/ 100

Very low

2,564 residues

Confidence breakdown

Very high(≥ 90)12%
Confident(70–90)9%
Low(50–70)2%
Very low(< 50)78%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

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