SHH

Chr 7q36.3

sonic hedgehog signaling molecule

Aliases:: HHG1, SMMCI, TPT, TPTPS, MCOPCB5
MANE:: ENST00000297261.7

OMIM: 600725 ↗NCBI: 6469 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

SHH · Q15465

v62025-08-01

Predicted Aligned Error matrix for SHH — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

78.4/ 100

Confident

462 residues

Confidence breakdown

Very high(≥ 90)47%
Confident(70–90)27%
Low(50–70)10%
Very low(< 50)17%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.