SLC34A2

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Childhood interstitial lung disease

  BIALLELIC, autosomal or pseudoautosomal

• Familial pulmonary fibrosis

  BIALLELIC, autosomal or pseudoautosomal

• Pulmonary alveolar microlithiasis

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• pulmonary alveolar microlithiasis

  0.78

• lung adenocarcinoma

  0.41

• non-small cell lung carcinoma

  0.40

• squamous cell lung carcinoma

  0.37

• acute myeloid leukemia

  0.34

• colorectal adenocarcinoma

  0.32

• external ear disorder

  0.31

• complex regional pain syndrome

  0.31

• placenta praevia

  0.31

• placental abruption

  0.31

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)