SMG8

Chr 17q22

SMG8 nonsense mediated mRNA decay factor

Aliases:: FLJ10587, FLJ23205
MANE:: ENST00000300917.10

OMIM: 613175 ↗NCBI: 55181 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

SMG8 · Q8ND04

v62025-08-01

Predicted Aligned Error matrix for SMG8 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

73.9/ 100

Confident

991 residues

Confidence breakdown

Very high(≥ 90)43%
Confident(70–90)26%
Low(50–70)8%
Very low(< 50)24%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.