SNCA

Chr 4q22.1

synuclein alpha

Aliases:: NACP, PD1
MANE:: ENST00000394991.8

OMIM: 163890 ↗NCBI: 6622 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

SNCA · P37840

v62025-08-01

Predicted Aligned Error matrix for SNCA — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

75.2/ 100

Confident

140 residues

Confidence breakdown

Very high(≥ 90)29%
Confident(70–90)34%
Low(50–70)24%
Very low(< 50)13%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.