SPOP

Chr 17q21.33

speckle type BTB/POZ protein

Aliases:: TEF2, BTBD32
MANE:: ENST00000504102.6

OMIM: 602650 ↗NCBI: 8405 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

SPOP · O43791

v62025-08-01

Predicted Aligned Error matrix for SPOP — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

90.1/ 100

Very high

374 residues

Confidence breakdown

Very high(≥ 90)77%
Confident(70–90)12%
Low(50–70)7%
Very low(< 50)4%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.