TACSTD2

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Corneal abnormalities

  BIALLELIC, autosomal or pseudoautosomal

• Corneal dystrophy

  BIALLELIC, autosomal or pseudoautosomal

• Structural eye disease

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• gelatinous drop-like corneal dystrophy

  0.73

• breast cancer

  0.61

• triple-negative breast carcinoma

  0.55

• non-small cell lung carcinoma

  0.55

• neoplasm

  0.51

• breast neoplasm

  0.47

• urothelial carcinoma

  0.44

• cartilage disease

  0.32

• cancer

  0.32

• small cell lung carcinoma

  0.31

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)