AlphaFold predicted structure
TBATA · Q96M53
Mean pLDDT
60.5/ 100
Low
351 residues
Confidence breakdown
- Very high(≥ 90)14%
- Confident(70–90)14%
- Low(50–70)34%
- Very low(< 50)38%
Open interactive 3D viewer
AlphaFold (Jumper et al., 2021) · CC BY 4.0
TBATA
Chr 10q22.1thymus, brain and testes associated
- Aliases:
- FLJ32820, spatial
- MANE:
- ENST00000456372.4
Annotations refreshed 9 hours ago.
Predicted protein structure
Clinical relevance (Genomics England PanelApp)
Moderate Evidence (Amber)
Familial Hirschsprung Disease
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Disease associations (Open Targets)
pyelonephritis
0.25Hirschsprung disease
0.21Aganglionic megacolon
0.11type 2 diabetes mellitus
0.04lymphoid neoplasm
0.03Abnormality of the skeletal system
0.03corneal neovascularization
0.03amyotrophic lateral sclerosis
0.03neuroendocrine neoplasm
0.03ovarian neoplasm
0.03
Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.
Protein function (UniProt)
Protein TBATA
May play a role in spermatid differentiation. Modulates thymic stromal cell proliferation and thymus function