TMEM72

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Moderate Evidence (Amber)

• Cystic kidney disease

  BIALLELIC, autosomal or pseudoautosomal

• Renal ciliopathies

  BIALLELIC, autosomal or pseudoautosomal

• Tubulointerstitial kidney disease

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• hypertensive disorder

  0.37

• corneal neovascularization

  0.29

• Abnormality of refraction

  0.28

• pernicious anemia

  0.28

• cardiovascular disorder

  0.28

• malignant renal pelvis neoplasm

  0.25

• nephronophthisis

  0.25

• stroke disorder

  0.23

• alcohol drinking

  0.23

• abscess

  0.22

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.