TMPRSS2

Chr 21q22.3

transmembrane serine protease 2

Aliases:: PRSS10
MANE:: ENST00000332149.10

OMIM: 602060 ↗NCBI: 7113 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

TMPRSS2 · O15393

v62025-08-01

Predicted Aligned Error matrix for TMPRSS2 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

79.4/ 100

Confident

492 residues

Confidence breakdown

Very high(≥ 90)50%
Confident(70–90)27%
Low(50–70)6%
Very low(< 50)17%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.