TRAPPC9

Predicted protein structure

Clinical relevance (Genomics England PanelApp)

Diagnostic Grade (Green)

• Clefting

  BIALLELIC, autosomal or pseudoautosomal

• DDG2P

  BIALLELIC, autosomal or pseudoautosomal

• Fetal anomalies

  BIALLELIC, autosomal or pseudoautosomal

• Intellectual disability

  BIALLELIC, autosomal or pseudoautosomal

• Severe microcephaly

  BIALLELIC, autosomal or pseudoautosomal

Disease associations (Open Targets)

• intellectual disability, autosomal recessive 13

  0.77

• autosomal recessive non-syndromic intellectual disability

  0.63

• intellectual disability-obesity-brain malformations-facial dysmorphism syndrome

  0.53

• hereditary disease

  0.52

• Abnormality of the nervous system

  0.45

• autism spectrum disorder

  0.41

• Intellectual disability

  0.41

• Intellectual disability - obesity - brain malformations - facial dysmorphism

  0.37

• cervical carcinoma

  0.35

• pyelonephritis

  0.31

Score is the Open Targets composite evidence score (0-1). Higher = stronger gene-disease association.

Protein function (UniProt)

Diseases associated with TRAPPC9

Curated MONDO disease pages that list TRAPPC9 among their top associated genes.

• cervical carcinomaRare