TREM2

Chr 6p21.1

triggering receptor expressed on myeloid cells 2

Aliases:: TREM-2, Trem2a, Trem2b, Trem2c
MANE:: ENST00000373113.8

OMIM: 605086 ↗NCBI: 54209 ↗Ensembl ↗

Predicted protein structure

AlphaFold predicted structure

TREM2 · Q9NZC2

v62025-08-01

Predicted Aligned Error matrix for TREM2 — diagonal shows residue index, colour shows pairwise prediction confidence (lower is better) — Predicted Aligned Error

Mean pLDDT

76.8/ 100

Confident

230 residues

Confidence breakdown

Very high(≥ 90)50%
Confident(70–90)12%
Low(50–70)17%
Very low(< 50)22%

Open interactive 3D viewer

AlphaFold (Jumper et al., 2021) · CC BY 4.0

Detailed annotations are loading.

We have HGNC metadata for this gene, but the deeper annotations (ClinVar, gnomAD, PanelApp, …) populate when someone uses the GenoLens extension to look up this gene. Install the extension or check back in a moment.